As we age, our vulnerability to both chronic and infectious disease increases a thousand fold. Chronic pain, dementia, and cancer aren’t much of a concern when we’re young, but with age such maladies appear in rapid succession. Research has identified underlying processes for this vulnerability, and targeting these processes both extends life and delays the onset of all these diseases. Identifying therapies that change processes of aging in humans thus represents the biggest lever our race has on health and disease. The field is poised for radical impact, but making this reality will take a lot of effort.

The Apprenticeship is a training ground for people who can make that happen. From day one, apprentices get hands-on experience identifying bottlenecks for the field, and designing projects to address these bottlenecks. We produce roadmaps and materials to accelerate progress, with a focus on calibrated technical insight distilled into shovel-ready action plans.